The same day, the University of Münster, Germany, and life technology companies announced the collaboration team, and by measuring the bacteria from one patient genomic sequence. Life Technologies, Inc. is a senior manufacturer of DNA sequencing.
June 3, the news reached the two applications is biological information held in the UK and public health microbiology meeting, the participants of scientists, Beijing Genomics Institute immediately available genome sequence of the bacteria. Spain, a bioinformatics company soon on the new E. coli genome sequence for automatic analysis, the company's researchers Kui wrote in his blog: "In less than 24 hours, we obtained data assembly sequence, and sequence interpretation. This is a good example of the research. "
"Science," the article pointed out that the analysis showing a picture of alarming. DNA sequence of a new pathogen in Germany showed that E. coli bacteria is not a typical genus.
New pathogens and the genome of E. coli 55989 over 93% of homology, E. coli 55989 is a 2002 from the Central African Republic, chronic diarrhea, HIV-positive patients is isolated. German National Reference Laboratory Luosabotan E. coli, said E. coli is the intestine hemorrhagic Escherichia coli cluster type genus of a class, that E. coli can form biofilms in vivo, but also to adapt in Escherichia coli in the human gut aggregation;, however, does not normally carry EHEC Shiga toxin genes, "This new virus appears to be the Shiga toxin gene in a typical colorectal bleeding bacillus. "
Shigella is a type of Gram-negative bacteria, is the most common human pathogen of bacillary dysentery, also known as Shigella. Although E. coli is the human intestinal flora component, and usually do not cause disease, but some strains of E. coli and dangerous when combined will produce Shiga toxin, Shiga toxin into the intestinal lining cells and prevent the protein synthesis.
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